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fadM [2019-02-01 12:03:43]
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fadM [2019-02-01 12:03:43]

fatty acid degradation, similar to proline dehydrogenase
Locus
BSU32850
Isoelectric point
9.38
Molecular weight
34.30 kDa
Protein length
302 aa Sequence Blast
Gene length
909 bp Sequence Blast
Function
fatty acid degradation
Product
unknown
Essential
no
Synonyms
yusM
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Lipid metabolism → Utilization of lipids → Utilization of fatty acids
  • Lifestyles → Sporulation → Sporulation proteins → Newly identified sporulation proteins (based on transcription profiling)

    • Gene

    Coordinates
    3,372,740 → 3,373,648

    The protein

    Catalyzed reaction/ biological activity

  • L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor (according to Swiss-Prot)

    • Protein family

  • proline dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • PutB

    • Expression and Regulation

    Operons

    Genes
    fadM-fadN-fadA-fadE
    Description
    PubMed

    Regulatory mechanism

  • FadR: repression, PubMed, in FadR regulon
  • SdpR: activation, PubMed, in SdpR regulon

    • Regulation

  • fadM: induced by long-chain fatty acids (FadR) PubMed
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    Biological materials

    Mutant

  • MGNA-A598 (yusM::erm), available at the NBRP B. subtilis, Japan
  • BKE32850 (ΔfadM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCGACTCCCTCCCGCCG, downstream forward: _UP4_TGAAAGCAGCCGTGGGAAGC
  • BKK32850 (ΔfadM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCGACTCCCTCCCGCCG, downstream forward: _UP4_TGAAAGCAGCCGTGGGAAGC

    • References

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